Utilize a problem-oriented approach to the diagnosis of diseases of horses, cattle, sheep, and goats. Large Animal Internal Medicine, 6th Edition covers the diagnosis and management of disease in both ruminant and equine internal medicine. As the first veterinary internal medicine text to use a problem-based approach, it offers discussions of over 150 clinical signs and manifestations, as well as comprehensive coverage of laboratory and diagnostic testing. New to this edition is a versatile online reference platform and coverage of conditions that exist in Europe, Central and South America, Australia, and New Zealand. In addition, thoroughly revised and updated content includes new vaccines and vaccination protocols; the most current laboratories for DNA, genetic, and PCR testing; and colostrum supplements and replacers. It’s everything you need to stay up to date with the latest information on preventing and treating disease in large animals.

• Discussions of over 150 clinical signs or manifestations of diseaseprovide you with a problem-based approach to diagnosis based on what you’ve observed and what laboratory tests reveal.
• Causes of Presenting Signs boxes offer quick access to the common, less common, and uncommon diseases associated with manifestations or signs of disease.
• Causes of Abnormal Laboratory Values boxes highlight the possible interpretations of abnormalities in clinical chemistry, hematology, blood proteins, and clotting tests.
• More than 200 expert authors contribute information in their areas of expertise for the most current, authoritative information on each topic.

PART I: HISTORY, PHYSICAL EXAMINATION, AND MEDICAL RECORDS
1. Ruminant History, Physical Examination, and Records
2. Equine History, Physical Examination, Records, and Recognizing Abuse or Neglect in Patients

PART II: MANIFESTATIONS OF DISEASE
3. Pain
4. Alterations in Body Temperature
5. Alterations in Respiratory Function
6. Alterations in Cardiovascular and Hemolymphatic Systems
7. Alterations in Alimentary and Hepatic Function
8. Localization and Differentiation of Neurologic Diseases
9. Alterations in Body Weight or Size
10. Alterations in Urinary Function
11. Alterations in the Skin
12. Alterations in Sexual Function
13. Musculoskeletal Abnormalities
14. Collapse and Sudden Death

PART III: DISORDERS AND MANAGEMENT OF THE NEONATE
15. The Equine Peripartum Period
16. Assessment of the Newborn Foal
17. Manifestations and Management of Disease in Neonatal Foals
18. The Peripartum Ruminant
19. Initial Management and Clinical Investigation of Neonatal Ruminants
20. Manifestations and Management of Disease in Neonatal Ruminants
21. Colostrum and Milk Replacers

PART IV: COLLECTION OF SAMPLES AND INTERPRETATION OF LABORATORY TESTS
22. Clinical Chemistry Tests
23. Collection and Submission of Samples for Hematologic and Cytologic Studies
24. Alterations in the Erythron
25. Alterations in the Leukogram
26. Alterations in Blood Proteins
27. Alterations in Hemostasis
28. Collection and Analysis of Bone Marrow
29. Molecular Diagnostics

PART V: DISORDERS OF THE ORGAN SYSTEMS
30. Diseases of the Cardiovascular System
31. Diseases of the Respiratory System
32. Diseases of the Alimentary Tract
33. Diseases of Hepatobiliary System
34. Diseases of the Renal System
35. Diseases of the Nervous System
36. Mammary Gland Health
37. Diseases of the Hematopoietic and Hemolymphatic Systems
38. Diseases of the Bones, Joints, and Connective Tissues
39. Diseases of the Eye
40. Diseases of the Skin
41. Endocrine and Metabolic Diseases
42. Diseases of Muscle
43. Diseases of the Reproductive System

PART VI: PREVENTIVE AND THERAPEUTIC STRATEGIES
44. Critical Care and Fluid Therapy
45. Rational Antimicrobial Therapy
46. Biosecurity and Infection Control
47. Prevention, Detection, and Response to Transboundary (Foreign) Animal Diseases
48. Use of Biologics in the Prevention of Infectious Diseases
49. Parasite Control Programs
50. Nutrition of the Sick Animal

PART VII: CONGENTIAL, HEREDITARY, IMMUNOLOGIC, AND TOXIC DISORDERS
51. Genetic Disorders
52. Genetic Tests for Large Animals
53. Immunologic Disorders
54. Disorders Caused by Toxicants